Makers of generic drugs must show that they do not differ significantly from the "reference" drugs that they imitate. one aspect in which drugs might differ is their extent of absorption in the blood. The below table gives data taken from 20 healthy nonsmoking male subjects for on pair of drugs. This is a matched pairs design. numbers 1-20 were assigned at random to the subjects. subjects 1-10 received the generic drug first, and subjects 11-20 received the reference drug first. In all cases, a washout period separated the two drugs so that the first had disappeared from the blood before the subject took the second. Do the drugs differ significantly in absorption? Describe the procedure used in testing for significance. I tried doing a dotplot but that didn't work out too well. Am I to do the stemplot? subj ref drub gen drug 15 4108 1755 3 2526 1138 9 2779 1613 13 3852 2254 12 1833 1310 8 2463 2120 18 2059 1851 20 1709 1878 17 1829 1682 2 2594 2613 4 2344 2738 16 1864 2302 6 1022 1284 10 2256 3052 5 938 1287 7 1338 1930 14 1262 1964 11 1438 25498 1 1738 3340 19 1020 3050
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Answer:Step-by-step explanation:subj ref drub gen drug1 1738 33402 2594 26133 2526 11384 2344 27385 938 12876 1022 12847 1338 19308 2463 21209 2779 161310 2256 3052those are the 10 first ones, you want to calculate the mean of the absorption time for about drugs, you can do this by summing all the times and dividing it by the total of samples, in this case 10.for the reference drug the mean is 1999.8for the generic drug the mean is 2018.8which says that the generic drug is absorbed a little bit slower in mean, but this may be because our samples took other one first, so now we see the other 10, i will only put the math herefor the sample drug 2097.4for the generic drug 2240.66where i discarded the sample number 11 because there may be a error there.then in bout cases you can see that the generic drug is absorbed slowly.